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What would Wes Streeting need to do to become Prime Minister?

Former health minister 'to set out challenge' to become Labour leader in next week

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Wes Streeting arrives at the Progress Conference at Convene in London. Picture date: Saturday May 16, 2026.
Wes Streeting has been a vocal critic of Starmer from the backbenches since stepping down. Picture: Alamy

By William Mata

Wes Streeting is reportedly primed to launch a challenge to Sir Keir Starmer on the back of the Makerfield by-election.

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The former Labour health secretary said the prime minister should draw up a timetable for his departure if Andy Burnham wins the Greater Manchester seat.

Mr Streeting, who left the Cabinet last month after Labour's poor performance in the local elections, accused Sir Keir of not listening to the party or his Cabinet in a series of public appearances on Tuesday.

The Makerfield by-election will be on Thursday, June 18, with Mr Burnham, a potential leadership rival to the PM, looking to return to the Commons, which he would need to do to challenge Sir Keir.

The PM, who is currently at the G7 summit in France and missed Prime Minister's Questions on Wednesday, has responded by throwing his support behind Mr Burnham.

He has added that the Greater Manchester Mayor would have a "big role" in the government if elected, suggesting that he could return to the Cabinet after more than 15 years away.

Ilford North MP Mr Streeting is pushing for Sir Keir to step down, whatever the result in Makerfield.

Asked if he would challenge Sir Keir if the Greater Manchester Mayor does not win, he told LBC’s Andrew Marr show: “Yes, I believe we need a change of leadership, and if Andy Burnham isn’t back, I still believe we need that change of leadership.”

Here is how a leadership challenge could take shape.

Read also: Who is Wes Streeting? Labour health secretary set 'to challenge Starmer'

Wes Streeting
Wes Streeting has ambitions to become prime minister. Picture: Alamy

What would Wes Streeting need to do to challenge Sir Keir Starmer and become prime minister?

Mr Streeting is said to be primed to launch a leadership challenge at the beginning of next week, but would require the backing of 20% of Labour MPs to appear on the ballot.

If he was able to secure this many signatures, he would then be able to go to a head-to-head shoot-out against Sir Keir for Labour leadership.

As the existing prime minister, the prime minister's name would automatically be on the ballot.

Mr Streeting has insisted he has the backing of the 80 MPs required.

When quizzed about the possibility of a leadership challenge, Sir Keir said: “So very many times on my political journey, people have said to me it’s not possible.

“They said it’s not possible to turn the Labour Party around. It’s not possible to win an election.

“It’s not possible if you do win an election, to invest in your public services and stabilise the economy – wrong every time, and that’s why I intend not to walk away from this, but to carry on with what I was elected to do, which is to serve this country, bring back the change that people desperately need in their lives.”

Wes Streeting speaking about progressive capitalism at No1 Tower Place West, in central London. Picture date: Tuesday June 16, 2026.
Wes Streeting is considered a front runner to be the next Labour leader. Picture: Alamy