First patient gets Pfizer's anti-Covid pill designed to stop coronavirus replicating

1 September 2021, 17:06

The pharmaceutical company has begun patient trials.
The pharmaceutical company has begun patient trials. Picture: Alamy

By Emma Soteriou

The first patient has been given a dose of an anti-viral pill in a clinical trial by Pfizer - designed to stop coronavirus replicating once people start showing symptoms.

The drug, which has entered mid-to-late-stage trials, is intended to be taken when individuals first start to show symptoms of Covid-19.

Around 1,140 participants have been enrolled in the randomised, double-blind patient trials. Those involved will receive either the pill or placebo every 12 hours for five days.

The pill is designed to block the activity of a key enzyme that is needed for coronavirus to replicate.

It comes as Pfizer has been up against the US-based Merck & Co Inc and the Swiss Roche Holding AG to develop the first anti-viral pill against the disease.

To date, Gilead Sciences Inc's remdesivir, administered intravenously, is the only approved antiviral treatment for Covid-19 in the United States.

Read more: Mu: New Covid strain designated variant of interest by WHO

Read more: Teenage Covid victim branded 'Satan' by anti-vaxxers for telling youngsters to get jab

Pfizer-BioNTech Covid-19 vaccine approved for use in 12 to 15-year-olds

The study is part of "a global clinical development programme, consisting of multiple ongoing and planned clinical trials" to evaluate the potential use in a broad population of patients, the pharmaceutical company said.

If the trial proves successful, Pfizer suggested in July that it would file for potential emergency use authorisation further down the line.

The company's chairman, Albert Bourla, tweeted that he was "pleased" to share that trials had moved forward for the pill specifically designed to combat Covid in non-hospitalised, low-risk adults.

Trials for those at an increased risk of progressing to severe illness if they caught Covid began in July.

Meanwhile, Pfizer's clinical trials for the pill first began in March 2021.

More than 90 million Brits have been vaccinated against the virus so far, with booster jabs also expected in coming months for those most vulnerable.

More Latest News

See more More Latest News

Donald Trump has called for the "unconditional surrender" of Iran

Trump calls for 'unconditional surrender' from Iran - hours after claiming to know supreme leader's location

A man walks past empty shelves in a branch of the Co-op in Manchester following the major cyber attack.

Major UK supermarket offering 25% off £40 shops in ‘thank you’ to members after cyber attack

Cyclists are sending a record amount of video footage to police after being overtaken too closely by motorists, new figures show.

Cyclists sending record number of videos to police after being overtaken too closely by drivers, figures show

Exclusive
Suspended chief constable Nick Adderley

Disgraced police chief Nick Adderley slammed for ‘unacceptable’ role in Harry Dunn case

Grenfell tower cover in white tarpaulin

Government pressed over why Grenfell cladding ‘crooks’ not behind bars

Donald Trump is said to be considering joining Israel in striking Iran

Trump 'considering US strike on Iran' - hours after claiming to know supreme leader's location

The biggest lottery prize the UK has seen could still be won after Tuesday’s EuroMillions draw had no winners.

EuroMillions record £208 million jackpot won by single ticket holder

Referee David Coote has been sacked.

Sacked Premier League referee David Coote charged by FA over ‘German c***’ Jurgen Klopp comments

Exclusive
Relatives of the Palestinians killed in Israeli attack, mourn as they carry the bodies to Nasser hospital for funeral procedures in Khan Yunis

Israeli Ambassador denies IDF is 'targeting civilians' as medics say 59 Palestinians killed by IDF at aid distribution centre

The man given a restraining order for stalking British number one Emma Raducanu has been caught trying to obtain tickets for this summer’s Wimbledon.

Emma Raducanu stalker caught trying to obtain Wimbledon tickets after tennis star was left 'shaken' by 'fixated' man

Eight-month-old Mabli had just said a final goodbye to her paternal grandmother Betty Hall, who was receiving end-of-life care at the Withybush Hospital in Haverfordwest.

Driver who ran over and killed eight-month-old baby in pram has sentence cut

Exclusive
UK 'not going to be involved' in 'protecting' Israel during Iran conflict, Israeli ambassador confirms

UK 'not going to be involved' in 'protecting' Israel during Iran conflict, Israeli ambassador tells LBC

Abortion rights actvists gather outside the parliament in support of decriminalisation.

MPs vote to decriminalise abortion in England and Wales in historic Commons vote

New York City Comptroller Brad Lander is placed under arrest by Immigration and Customs Enforcement (ICE) and FBI agents outside federal immigration court on Tuesday, June 17, 2025, in New York.

New York mayoral candidate Brad Lander arrested and detained by ICE amid Donald Trump's immigration crackdown

Trump not planning to attack Iran, Starmer insists as US President says he won't kill Supreme Leader 'for now'

Trump 'not planning to attack Iran', Starmer insists as US President says he won't kill Supreme Leader 'for now'

Dame Katherine Grainger

Olympic gold medallist Katherine Grainger and former Cabinet Secretary Simon Case given peerages